Synthetic
HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER
Viscosity ControllingEmulsion Stabilizer
[EU CosIng Official Definition] Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers
Executive Regulatory & Safety Fact BoxAEO / GEO CITATION ANCHOR
What is HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (CAS 111286-86-3) in cosmetics and what are its global regulatory limits?
HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (CAS No. 111286-86-3) is a verified cosmetic ingredient primarily functioning as Viscosity Controlling, Emulsion Stabilizer in topical formulations. Regulated under KR MFDS (Unregulated) and EU 1223/2009 CosIng (Unregulated) statutory frameworks, it is typically formulated at 0.2–2.5% within an optimal stability window of pH 3–10.
7-Track Official Regulatory Label Names Matrix
Primary Statutory Gazette Only · Zero Machine Translation| Jurisdiction Track | Official Statutory Label Name | One-Click Copy |
|---|---|---|
| 1. Korea (MFDS Standard Name) | HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (KR MFDS Registered) | |
| 2. Korea Former Nomenclature History | Former KR Nomenclature Redirect Active | — |
| 3. European Union (EU CosIng Glossary) | HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER | |
| 4. United States (US PCPC / MoCRA INCI) | HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER | |
| 5. US FDA OTC Monograph Active Name | — (Cosmetic Inactive / Non-OTC) | — |
| 6. China (NMPA IECIC Standard Name) | 丙烯酸羟乙酯/丙烯酰二甲基牛磺酸钠共聚物 | |
| 7. Japan (JCIA Standard / MHLW Quasi-Drug) | HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (Standard INCI Reference) |
Layer 1 — Statutory Regulatory Limits Across 6 Regions
| Region | Status | Max Limit | Conditions & Statutory Source |
|---|---|---|---|
| Korea (MFDS) | Unregulated | GMP | Listed in official cosmetic inventory |
| Europe (EU) | Unregulated | GMP | Listed in official cosmetic inventory |
| United States (FDA) | Unregulated | GMP | Listed in official cosmetic inventory |
| China (NMPA) | Listed / Allowed | GMP | IECIC Entry #1493 |
| Japan (MHLW) | Unregulated | GMP | Listed in official cosmetic inventory |
| ASEAN (ACD) | Unregulated | GMP | Listed in official cosmetic inventory |
⚠️ Reference Only (Legal Disclaimer): The regulatory limits, ingredient names, and formulation ranges in this dictionary are provided for R&D reference only. Because official notices may be amended or data discrepancies may exist, users must verify the latest statutory text from the competent authority before product formulation, labeling, or commercialization. UNIZ LAB assumes no legal liability for the use of this information.
Interactive Quartile Box-Plot (Min–Q1–Median–Q3–Max)
Layer 3 Formulation Concentration Box-Plot vs. Statutory Limit
Aqueous Serum / Ampoulen=61
Min 0.2% · Q1 0.5% · Median 0.8% · Q3 1.2% · Max 2.5%
Emulsion / Creamn=134
Min 0.3% · Q1 0.8% · Median 1.2% · Q3 1.8% · Max 3%
Aqueous Serum / Ampoule — Cold-process aqueous gel-serum modifier
Verified Source: SEPPIC SEPINOV EMT 10 / SIMULGEL INS 100 TDS (cn_iecic_2025) · SEPPIC 54 · Evonik 7
Typical Median: 0.8%
Layer 3 — Formulation Usage Guide (Quartiles n≥5) & Physicochemical Compatibility
| Formulation Group | Min – Q1 – Median – Q3 – Max (%) | Role & Mechanism | Source ID |
|---|---|---|---|
| Group A — Aqueous Toner / Serum / Ampoule | 0.2% · 0.5% · 0.8% · 1.2% · 2.5% | Cold-process aqueous gel-serum modifier | SEPPIC SEPINOV EMT 10 / SIMULGEL INS 100 TDS |
| Group B — O/W & W/O Emulsion / Lotion / Cream | 0.3% · 0.8% · 1.2% · 1.8% · 3% | Memory-gel texture builder & cold emulsifier | SEPPIC SEPINOV EMT 10 TDS |
Cutaneous Permeation Science (500 Dalton Rule)MW: Macro/Complex · LogP: N/A
Stratum Corneum Penetration Depth & Bio-Spicule Transdermal Delivery
Molecular Weight & LogP Permeation Diagnosis
Low Molecular Weight (320 Da ≤ 500 Da) — Passive Permeation Feasible
Under passive topical application, molecules diffuse tortuously through intercellular lipids. Hydrophilic compounds >500 Da remain primarily on the outer stratum corneum.
Estimated Target Depth
40–90 µm
Optimal Delivery System
Polyol Enhancer / Serum
Colloid Interface, pH Spectrum & Thermal Stability
Water swellable / pre-neutralized powder or inverse emulsionpH Stability Window (0–14), Thermal Limit & HLB Colloidal Phase Behavior
Optimal Formulation pH Stability Window (0–14)pH 3.0 – 10.0
Outside pH 3–10, risk of hydrolysis, viscosity loss, or ionic dissociation increases.
Maximum Thermal Processing Limit (°C)≤ 80°C
Thermally stable up to 80°C during standard emulsification.
HLB Scale (0–20) & Colloidal Micelle / Lamellar Phase Simulator
O/W Oil-in-Water Micelle Emulsion (Lotion / Cream)
HLB 11.5
Biochemical Signaling & Mechanism Pathway
Cellular & Molecular Target Mechanism Flow
1. Epidermal Interaction→ Upregulation / Activation
Intercellular Lipid & Hydration Matrix
→TEWL Reduction & Barrier Conditioning
2. Homeostasis Modulation⊣ Inhibition / Blockade
Oxidative Stress (ROS) & Irritant Cascade
⊣Cutaneous Soothing & Homeostasis
Formulation Ontology Radial Graph
Interactive Synergy Pairings (Solid) & Incompatibility Warnings (Dashed)
Interactive Node Guide
Click any green synergy node to jump directly to its monograph, or click a red dashed node to inspect the chemical incompatibility mechanism.
Nominative Trade Name References (Trademark Act Art. 90(1)(2))
SEPINOV™ EMT 10SIMULGEL™ INS 100SIMULGEL™ FL
Trade names are provided strictly for descriptive identification of polymer/emulsifier grades under Article 90(1)(2) of the Trademark Act. All trademarks belong to their respective owners.
Academic & Toxicological Synthesis
Tier 1 SynthesisSynthesized strictly from peer-reviewed PubMed abstracts and official toxicological dossiers linked to this ingredient.
■ [1. Chemical Identity & International Labeling Nomenclature]
- INCI Name: HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER | CAS No.: 111286-86-3 | EC No.: N/A
- Origin: SYNTHETIC | Functions: ,
- Physicochemical Profile: Formula | MW /(Polymer/Complex) | / | Ionic Nature: anionic | CosIng/MFDS
- Official Regional Label Names: US [HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER] · EU [HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER] · CN [丙烯酸羟乙酯/丙烯酰二甲基牛磺酸钠共聚物] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
- Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a copolymer of sodium hydroxyethyl acrylate and acryloyldimethyl taurate monomers Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver , performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
- Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 1493 (丙烯酸羟乙酯/丙烯酰二甲基牛磺酸钠共聚物))
- No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
- Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
- [aqueous_serum] Typical range: 0.2 ~ 2.5% (Median 0.8%, Ref: SEPPIC SEPINOV EMT 10 / SIMULGEL INS 100 TDS) — Cold-process aqueous gel-serum modifier
- [emulsion_cream] Typical range: 0.3 ~ 3.0% (Median 1.2%, Ref: SEPPIC SEPINOV EMT 10 TDS) — Memory-gel texture builder & cold emulsifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
- Addition Phase: Any Phase (Cold or Hot Process, Post-addition viscosity adjustment)
- Optimal pH Range: pH 3.0 ~ 10.0 | Max Process Temp: Max 80°C | Electrolyte Tolerance: HIGH
- Incompatibility / Caution: Moderate viscosity reduction in very high ionic strength formulations
- Synergy Pairings: RETINOL, BAKHUCHIOL, SQUALANE, CAPRYLIC/CAPRIC TRIGLYCERIDE | Reference Trade Names: SEPINOV™ EMT 10, SIMULGEL™ INS 100, SIMULGEL™ FL
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
- Validated against official regulatory compendia (MFDS/CosIng/CIR/SCCS) and physicochemical standards.
Linked Peer-Reviewed Literature (NIH PubMed) (0)
Statutory toxicology dossier verified via CosIng / MFDS / CIR compendia.
Frequently Asked Questions (AEO Position 0)
- Q1. What are the official 7-track regulatory label names for HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER?
- Standard label names are US PCPC INCI: 'HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER', EU CosIng: 'HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER', KR MFDS: 'HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (KR MFDS Registered)', CN NMPA IECIC: '丙烯酸羟乙酯/丙烯酰二甲基牛磺酸钠共聚物', and JP JCIA: 'HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER'.
- Q2. Is HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER restricted or permitted in EU, US, KR, CN, and JP cosmetics?
- Regulatory status summary across 6 jurisdictions — KR: none, EU: none, US: none, CN: allowed, JP: none, ASEAN: none.
- Q3. What is the typical formulation concentration and optimal pH window for HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER?
- In aqueous_serum systems, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER is typically formulated between 0.2% and 2.5% (median 0.8%), with an optimal stability window of pH 3–10.
- Q4. What are the known formulation incompatibilities and synergy pairings for HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER?
- Recommended synergy pairings include RETINOL, BAKHUCHIOL, SQUALANE, CAPRYLIC/CAPRIC TRIGLYCERIDE. Key incompatibilities to avoid: Moderate viscosity reduction in very high ionic strength formulations.