SSOT v2.01 Substance = 1 Canonical Document · 6-Region Primary Statutory Law · 100% GFW-Safe
4-Locale Live (EN · KO · ZH · JA)
The Global Cosmetic Ingredient & Regulatory Encyclopedia
37,845 verified cosmetic substances · 7-Track Official Regional Nomenclature (EU/US/US OTC/KR/CN/JP) · Statutory Limits (Layer 1) · SCCS/CIR/IECIC Safety Thresholds (Layer 2) · Formulation Quartiles & Incompatibility Warnings (Layer 3).
600+INCICAS
Total Verified Ingredients
37,845
15,414 Validated CAS · 0 Drift
6-Region Regulatory Matrix
66,975
MFDS API Rows + 8,965 CN IECIC
Linked PubMed Papers
8,994
171 Tier-1 Deep Monographs
100% GFW-Safe · Static Sharded
64 Shards
310 Layer-3 Guided Actives
Tool 01 · BOM & 7-Label Scanner0.1s Instant
Multi-Region BOM Regulatory & 7-Track Label Converter
Paste any INCI BOM to check 6-region statutory limits, CN IECIC historical max, incompatibility alerts, and convert into official KR/EU/US/CN/JP label strings.
Launch BOM Regulatory Scanner →
Tool 02 · HLB & CompatibilityInteractive SVG
Emulsion Required HLB Calculator & Incompatibility Checker
Calculate Required HLB from oil phase ratios, simulate emulsifier blends on a live gauge, and detect pH/electrolyte/chelate crashes.
Launch HLB & Compatibility Studio →
Tool 03 · Deformulation Studio1% Cutoff AI-Free
1% Cutoff Detector & Deformulation % Range Estimator
Automatically detects the 1% labeling threshold and estimates formulation concentration intervals (%) using Layer 1 limits and Layer 3 quartiles.
Launch Deformulation Estimator →
Global Ingredient Encyclopedia Directory (37,845 Canonical Substances)
Filter by Regional Trend, Function (75), Origin (8), and Monograph Depth (Tier 1–3) · Zero Machine Translation of Statutory Names
HYDROLYZED SPONGE
L3T1
CAS: —Skin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →BISABOLOL
L3T1
CAS: 515-69-5FragranceSkin ConditioningSynthetic
KR:iEU:✓CN:✓JP:!US:✓ASEAN:✓
View →TOCOPHERYL ACETATE
L3T1
CAS: 7695-91-2AntioxidantSkin ConditioningVitamin / Coenzyme
KR:✓EU:✓CN:✓JP:!US:✓ASEAN:✓
View →ALLANTOIN
L3T1
CAS: 97-59-6Skin ConditioningSkin ProtectingSynthetic
KR:✓EU:✓CN:✓JP:!US:!ASEAN:✓
View →CAFFEINE
L3T1
CAS: 58-08-2Skin ConditioningFragranceSynthetic
KR:✓EU:✓CN:✓JP:!US:✓ASEAN:✓
View →CERAMIDE NP
L3T1
CAS: 34354-88-6Hair ConditioningSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →GLYCERIN
L3T1
CAS: 56-81-5Hair ConditioningHumectantSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →PANTHENOL
L3T1
CAS: 81-13-0AntistaticHair ConditioningVitamin / Coenzyme
KR:iEU:✓CN:✓JP:!US:✓ASEAN:✓
View →RETINOL
L3T1
CAS: 68-26-8Skin ConditioningVitamin / Coenzyme
KR:iEU:!CN:iJP:✓US:✓ASEAN:!
View →SALICYLIC ACID
L3T1
CAS: 69-72-7Sebum ControlHair ConditioningSynthetic
KR:!EU:!CN:!JP:!US:!ASEAN:!
View →SODIUM HYALURONATE
L3T1
CAS: 9067-32-7HumectantSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →TOCOPHEROL
L3T1
CAS: 54-28-4AntioxidantFragranceVitamin / Coenzyme
KR:!EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →SQUALANE
L3T1
CAS: 111-01-3Hair ConditioningSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ZINC OXIDE
L3T1
CAS: 1314-13-2AntimicrobialBulkingMineral / Inorganic
KR:!EU:!CN:!JP:iUS:!ASEAN:!
View →BAKUCHIOL
L3T1
CAS: 10309-37-2AntimicrobialAntioxidantSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →KAOLIN
L3T1
CAS: 1332-58-7AbrasiveAbsorbentMineral / Inorganic
KR:✓EU:iCN:✓JP:✓US:✓ASEAN:✓
View →NIACINAMIDE
L3T1
CAS: 98-92-0SmoothingVitamin / Coenzyme
KR:iEU:✓CN:iJP:iUS:✓ASEAN:✓
View →WATER
L3T1
CAS: 7732-18-5Skin ConditioningSolventPlant / Botanical
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ETHYLHEXYL SALICYLATE
L3T1
CAS: 118-60-5UV FilterLight StabilizerSynthetic
KR:!EU:!CN:!JP:✓US:✓ASEAN:✓
View →ETHYLPARABEN
L3T1
CAS: 120-47-8FragrancePreservativeSynthetic
KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓
View →ZINC PCA
L3T1
CAS: 68107-75-5HumectantSkin ConditioningSynthetic
KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓
View →ASCORBIC ACID
L3T1
CAS: 50-81-7AntioxidantpH AdjusterVitamin / Coenzyme
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →BARIUM SULFATE
L3T1
CAS: 7727-43-7ColorantOpacifyingMineral / Inorganic
KR:✓EU:iCN:✓JP:✓US:✓ASEAN:✓
View →BEESWAX
L3T1
CAS: 8006-40-4FragranceSkin ConditioningAnimal-Derived
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CAPRYLIC/CAPRIC TRIGLYCERIDE
L3T1
CAS: 73398-61-5FragranceSolventSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →DMDM HYDANTOIN
L3T1
CAS: 6440-58-0PreservativeSynthetic
KR:!EU:!CN:!JP:✓US:✓ASEAN:✓
View →OCTOCRYLENE
L3T1
CAS: 6197-30-4UV FilterLight StabilizerSynthetic
KR:!EU:!CN:!JP:✓US:!ASEAN:✓
View →TRANEXAMIC ACID
L3T1
CAS: 1197-18-8AstringentSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →1,2-HEXANEDIOL
L3T1
CAS: 6920-22-5Skin ConditioningSolventSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →3-O-ETHYL ASCORBIC ACID
L3T1
CAS: 86404-04-8Skin ConditioningVitamin / Coenzyme
KR:iEU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ACETYL HEXAPEPTIDE-8
L3T1
CAS: 616204-22-9HumectantSkin ConditioningPeptide / Protein
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ALCOHOL
L3T1
CAS: 64-17-5AntimicrobialAstringentSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ALPHA-ARBUTIN
L3T1
CAS: 84380-01-8AntioxidantSkin BrighteningSynthetic
KR:iEU:!CN:iJP:✓US:✓ASEAN:!
View →BETAINE
L3T1
CAS: 107-43-7AntistaticHair ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →BHT
L3T1
CAS: 128-37-0AntioxidantFragranceSynthetic
KR:✓EU:!CN:✓JP:✓US:✓ASEAN:✓
View →BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE
L3T1
CAS: 187393-00-6Hair ConditioningUV FilterSynthetic
KR:!EU:!CN:!JP:!US:✕ASEAN:!
View →BIS-PEG-12 DIMETHICONE
L3T1
CAS: 102783-01-7Hair ConditioningSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →BUTYL METHOXYDIBENZOYLMETHANE
L3T1
CAS: 70356-09-1UV FilterLight StabilizerSynthetic
KR:!EU:!CN:!JP:✓US:✓ASEAN:✓
View →BUTYLENE GLYCOL
L3T1
CAS: 107-88-0HumectantFragranceSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →BUTYLPARABEN
L3T1
CAS: 94-26-8FragrancePreservativeSynthetic
KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓
View →CAPRYLYL GLYCOL
L3T1
CAS: 1117-86-8DeodorantHair ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CARBOMER
L3T1
CAS: 9003-01-4Viscosity ControllingEmulsion StabilizerSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CARRAGEENAN
L3T1
CAS: 9000-07-1Plant / Botanical
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CETEARYL ALCOHOL
L3T1
CAS: 8005-44-5OpacifyingEmollientSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CETEARYL GLUCOSIDE
L3T1
CAS: 246159-33-1EmulsifierCleansingSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CETYL ALCOHOL
L3T1
CAS: 36653-82-4FragranceOpacifyingSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CHLORPHENESIN
L3T1
CAS: 104-29-0AntimicrobialPreservativeSynthetic
KR:!EU:!CN:!JP:!US:✓ASEAN:!
View →CI 77491
L3T1
CAS: 1309-37-1ColorantMineral / Inorganic
KR:✓EU:iCN:✓JP:✓US:✓ASEAN:!
View →CITRIC ACID
L3T1
CAS: 77-92-9pH AdjusterChelatingSynthetic
KR:✓EU:!CN:✓JP:✓US:✓ASEAN:✓
View →COCAMIDOPROPYL BETAINE
L3T1
CAS: 97862-59-4AntistaticCleansingSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →CYCLOMETHICONE
L3T1
CAS: 69430-24-6Hair ConditioningSolventSynthetic
KR:✓EU:✕CN:✓JP:✓US:✓ASEAN:✓
View →CYCLOPENTASILOXANE
L3T1
CAS: 541-02-6Hair ConditioningSkin ConditioningSynthetic
KR:!EU:!CN:iJP:✓US:✓ASEAN:✓
View →DECYL GLUCOSIDE
L3T1
CAS: 54549-25-6CleansingEmulsion StabilizerSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →DEHYDROACETIC ACID
L3T1
CAS: 520-45-6PreservativeSynthetic
KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓
View →DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE
L3T1
CAS: 302776-68-7UV FilterLight StabilizerSynthetic
KR:!EU:!CN:!JP:!US:✕ASEAN:!
View →DIMETHICONE
L3T1
CAS: 63148-62-9Skin ConditioningSkin ProtectingSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →ETHYLHEXYL METHOXYCINNAMATE
L3T1
CAS: 5466-77-3UV FilterLight StabilizerSynthetic
KR:!EU:!CN:!JP:!US:!ASEAN:✓
View →ETHYLHEXYLGLYCERIN
L3T1
CAS: 70445-33-9DeodorantSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →FRAGRANCE
L3T1
CAS: —Synthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →GLUCONOLACTONE
L3T1
CAS: 90-80-2ChelatingSkin ConditioningSynthetic
KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓
View →| Standard INCI & Multi-Region Official Statutory Names | CAS No. | Functions & Origin | 6-Region Regulatory Status (KR·EU·US·CN·JP·ASEAN) | Monograph Tier |
|---|---|---|---|---|
HYDROLYZED SPONGE CN(IECIC): 水解海绵JP(JCIA): 加水分解カイメン | — | Skin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BISABOLOL CN(IECIC): 红没药醇 | 515-69-5 | FragranceSkin ConditioningSynthetic | KR:iEU:✓CN:✓JP:!US:✓ASEAN:✓ | L3 GuideTier 1 |
TOCOPHERYL ACETATE CN(IECIC): 生育酚乙酸酯JP(JCIA): 酢酸トコフェロール | 7695-91-2 | AntioxidantSkin ConditioningVitamin / Coenzyme | KR:✓EU:✓CN:✓JP:!US:✓ASEAN:✓ | L3 GuideTier 1 |
ALLANTOIN CN(IECIC): 尿囊素JP(JCIA): アラントイン | 97-59-6 | Skin ConditioningSkin ProtectingSynthetic | KR:✓EU:✓CN:✓JP:!US:!ASEAN:✓ | L3 GuideTier 1 |
CAFFEINE CN(IECIC): 咖啡因JP(JCIA): カフェイン | 58-08-2 | Skin ConditioningFragranceSynthetic | KR:✓EU:✓CN:✓JP:!US:✓ASEAN:✓ | L3 GuideTier 1 |
CERAMIDE NP CN(IECIC): 神经酰胺 NPJP(JCIA): セラミドＮＰ | 34354-88-6 | Hair ConditioningSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
GLYCERIN CN(IECIC): 甘油JP(JCIA): グリセリン | 56-81-5 | Hair ConditioningHumectantSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
PANTHENOL CN(IECIC): 泛醇JP(JCIA): パンテノール | 81-13-0 | AntistaticHair ConditioningVitamin / Coenzyme | KR:iEU:✓CN:✓JP:!US:✓ASEAN:✓ | L3 GuideTier 1 |
RETINOL CN(IECIC): 视黄醇JP(JCIA): レチノール | 68-26-8 | Skin ConditioningVitamin / Coenzyme | KR:iEU:!CN:iJP:✓US:✓ASEAN:! | L3 GuideTier 1 |
SALICYLIC ACID CN(IECIC): 水杨酸JP(JCIA): サリチル酸 | 69-72-7 | Sebum ControlHair ConditioningSynthetic | KR:!EU:!CN:!JP:!US:!ASEAN:! | L3 GuideTier 1 |
SODIUM HYALURONATE CN(IECIC): 透明质酸钠JP(JCIA): ヒアルロン酸Ｎａ | 9067-32-7 | HumectantSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
TOCOPHEROL CN(IECIC): 生育酚(维生素E)JP(JCIA): トコフェロール | 54-28-4 | AntioxidantFragranceVitamin / Coenzyme | KR:!EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
SQUALANE CN(IECIC): 角鲨烷JP(JCIA): スクワラン | 111-01-3 | Hair ConditioningSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ZINC OXIDE CN(IECIC): 氧化锌JP(JCIA): 酸化亜鉛 | 1314-13-2 | AntimicrobialBulkingMineral / Inorganic | KR:!EU:!CN:!JP:iUS:!ASEAN:! | L3 GuideTier 1 |
BAKUCHIOL JP(JCIA): バクチオール | 10309-37-2 | AntimicrobialAntioxidantSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
KAOLIN CN(IECIC): 高岭土 | 1332-58-7 | AbrasiveAbsorbentMineral / Inorganic | KR:✓EU:iCN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
NIACINAMIDE CN(IECIC): 烟酰胺JP(JCIA): ナイアシンアミド | 98-92-0 | SmoothingVitamin / Coenzyme | KR:iEU:✓CN:iJP:iUS:✓ASEAN:✓ | L3 GuideTier 1 |
WATER CN(IECIC): 水JP(JCIA): 水 | 7732-18-5 | Skin ConditioningSolventPlant / Botanical | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ETHYLHEXYL SALICYLATE CN(IECIC): 水杨酸乙基己酯 | 118-60-5 | UV FilterLight StabilizerSynthetic | KR:!EU:!CN:!JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ETHYLPARABEN CN(IECIC): 羟苯乙酯 | 120-47-8 | FragrancePreservativeSynthetic | KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ZINC PCA CN(IECIC): PCA 锌 | 68107-75-5 | HumectantSkin ConditioningSynthetic | KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ASCORBIC ACID CN(IECIC): 抗坏血酸(维生素C)JP(JCIA): アスコルビン酸 | 50-81-7 | AntioxidantpH AdjusterVitamin / Coenzyme | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BARIUM SULFATE CN(IECIC): 硫酸钡 | 7727-43-7 | ColorantOpacifyingMineral / Inorganic | KR:✓EU:iCN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BEESWAX CN(IECIC): 蜂蜡JP(JCIA): ミツロウ | 8006-40-4 | FragranceSkin ConditioningAnimal-Derived | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CAPRYLIC/CAPRIC TRIGLYCERIDE CN(IECIC): 辛酸/癸酸甘油三酯JP(JCIA): トリ（カプリル酸／カプリン酸）グリセリル | 73398-61-5 | FragranceSolventSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
DMDM HYDANTOIN CN(IECIC): DMDM 乙内酰脲 | 6440-58-0 | PreservativeSynthetic | KR:!EU:!CN:!JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
OCTOCRYLENE CN(IECIC): 奥克立林 | 6197-30-4 | UV FilterLight StabilizerSynthetic | KR:!EU:!CN:!JP:✓US:!ASEAN:✓ | L3 GuideTier 1 |
TRANEXAMIC ACID CN(IECIC): 凝血酸JP(JCIA): トラネキサム酸 | 1197-18-8 | AstringentSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
1,2-HEXANEDIOL CN(IECIC): 1,2-己二醇JP(JCIA): １，２－ヘキサンジオール | 6920-22-5 | Skin ConditioningSolventSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
3-O-ETHYL ASCORBIC ACID CN(IECIC): 3-邻-乙基抗坏血酸JP(JCIA): ３－Ｏ－エチルアスコルビン酸 | 86404-04-8 | Skin ConditioningVitamin / Coenzyme | KR:iEU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ACETYL HEXAPEPTIDE-8 CN(IECIC): 乙酰基六肽-8 | 616204-22-9 | HumectantSkin ConditioningPeptide / Protein | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ALCOHOL CN(IECIC): 乙醇JP(JCIA): エタノール | 64-17-5 | AntimicrobialAstringentSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ALPHA-ARBUTIN CN(IECIC): α-熊果苷JP(JCIA): α－アルブチン | 84380-01-8 | AntioxidantSkin BrighteningSynthetic | KR:iEU:!CN:iJP:✓US:✓ASEAN:! | L3 GuideTier 1 |
BETAINE CN(IECIC): 甜菜碱JP(JCIA): ベタイン | 107-43-7 | AntistaticHair ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BHT CN(IECIC): 丁羟甲苯JP(JCIA): ＢＨＴ | 128-37-0 | AntioxidantFragranceSynthetic | KR:✓EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE CN(IECIC): 双-乙基己氧苯酚甲氧苯基三嗪 | 187393-00-6 | Hair ConditioningUV FilterSynthetic | KR:!EU:!CN:!JP:!US:✕ASEAN:! | L3 GuideTier 1 |
BIS-PEG-12 DIMETHICONE CN(IECIC): 双-PEG-12 聚二甲基硅氧烷 | 102783-01-7 | Hair ConditioningSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BUTYL METHOXYDIBENZOYLMETHANE CN(IECIC): 丁基甲氧基二苯甲酰基甲烷JP(JCIA): ｔ－ブチルメトキシジベンゾイルメタン | 70356-09-1 | UV FilterLight StabilizerSynthetic | KR:!EU:!CN:!JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BUTYLENE GLYCOL CN(IECIC): 丁二醇JP(JCIA): ＢＧ | 107-88-0 | HumectantFragranceSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
BUTYLPARABEN CN(IECIC): 羟苯丁酯 | 94-26-8 | FragrancePreservativeSynthetic | KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CAPRYLYL GLYCOL CN(IECIC): 辛甘醇 | 1117-86-8 | DeodorantHair ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CARBOMER CN(IECIC): 卡波姆JP(JCIA): カルボマー | 9003-01-4 | Viscosity ControllingEmulsion StabilizerSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CARRAGEENAN | 9000-07-1 | Plant / Botanical | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CETEARYL ALCOHOL CN(IECIC): 鲸蜡硬脂醇JP(JCIA): セテアリルアルコール | 8005-44-5 | OpacifyingEmollientSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CETEARYL GLUCOSIDE CN(IECIC): 鲸蜡硬脂基葡糖苷 | 246159-33-1 | EmulsifierCleansingSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CETYL ALCOHOL CN(IECIC): 鲸蜡醇JP(JCIA): セタノール | 36653-82-4 | FragranceOpacifyingSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CHLORPHENESIN CN(IECIC): 氯苯甘醚JP(JCIA): クロルフェネシン | 104-29-0 | AntimicrobialPreservativeSynthetic | KR:!EU:!CN:!JP:!US:✓ASEAN:! | L3 GuideTier 1 |
CI 77491 US: IRON OXIDESCN(IECIC): CI 77491 | 1309-37-1 | ColorantMineral / Inorganic | KR:✓EU:iCN:✓JP:✓US:✓ASEAN:! | L3 GuideTier 1 |
CITRIC ACID CN(IECIC): 柠檬酸JP(JCIA): クエン酸 | 77-92-9 | pH AdjusterChelatingSynthetic | KR:✓EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
COCAMIDOPROPYL BETAINE CN(IECIC): 椰油酰胺丙基甜菜碱 | 97862-59-4 | AntistaticCleansingSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CYCLOMETHICONE CN(IECIC): 环聚二甲基硅氧烷 | 69430-24-6 | Hair ConditioningSolventSynthetic | KR:✓EU:✕CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
CYCLOPENTASILOXANE CN(IECIC): 环五聚二甲基硅氧烷JP(JCIA): シクロペンタシロキサン | 541-02-6 | Hair ConditioningSkin ConditioningSynthetic | KR:!EU:!CN:iJP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
DECYL GLUCOSIDE CN(IECIC): 癸基葡糖苷 | 54549-25-6 | CleansingEmulsion StabilizerSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
DEHYDROACETIC ACID CN(IECIC): 脱氢乙酸 | 520-45-6 | PreservativeSynthetic | KR:!EU:!CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE CN(IECIC): 二乙氨羟苯甲酰基苯甲酸己酯 | 302776-68-7 | UV FilterLight StabilizerSynthetic | KR:!EU:!CN:!JP:!US:✕ASEAN:! | L3 GuideTier 1 |
DIMETHICONE CN(IECIC): 聚二甲基硅氧烷JP(JCIA): ジメチコン | 63148-62-9 | Skin ConditioningSkin ProtectingSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
ETHYLHEXYL METHOXYCINNAMATE CN(IECIC): 甲氧基肉桂酸乙基己酯JP(JCIA): メトキシケイヒ酸エチルヘキシル | 5466-77-3 | UV FilterLight StabilizerSynthetic | KR:!EU:!CN:!JP:!US:!ASEAN:✓ | L3 GuideTier 1 |
ETHYLHEXYLGLYCERIN CN(IECIC): 乙基己基甘油JP(JCIA): エチルヘキシルグリセリン | 70445-33-9 | DeodorantSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
FRAGRANCE CN(IECIC): (日用)香精 | — | Synthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
GLUCONOLACTONE CN(IECIC): 葡糖酸内酯 | 90-80-2 | ChelatingSkin ConditioningSynthetic | KR:✓EU:✓CN:✓JP:✓US:✓ASEAN:✓ | L3 GuideTier 1 |
Formulation Masterclass · Rev.5.0 §5
Best-in-Class Functional Ingredient Masterclass (5 Core Formulation Skeletons)
Standard use levels (%), optimal pH windows, electrolyte tolerance, and processing know-how for the 5 foundational cosmetic skeletons
1. Thickeners & Rheology Modifiers
Trade names are provided strictly for descriptive identification of polymer/emulsifier grades under Article 90(1)(2) of the Trademark Act. All trademarks belong to their respective owners.Polyacrylate Crosspolymer-6
SEPIMAX™ ZENpH 2.0 ~ 8.0High (Suspends Spicule & Low-pH Acids)
High yield stress suspends Hydrolyzed Sponge (Spicule) and stabilizes low-pH AHA/Vitamin C serums.
Carbomer
Carbopol® 980 / Ultrez 21pH 5.5 ~ 9.0Low (Viscosity Crashes with Salts/Cations)
Requires neutralization (Arginine/Tromethamine/KOH). Incompatible with cationic actives & divalent salts.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Aristoflex® AVCpH 4.0 ~ 9.0Medium (Optimal for Mild Acidic Serums)
Pre-neutralized polymer giving velvety, non-tacky aqueous gels down to pH 4.0.
Xanthan Gum
Keltrol® CG-TpH 2.0 ~ 12.0High (Stable Across Temp, Salts & pH)
Pre-disperse in Butylene Glycol/Glycerin to prevent fish-eyes; combine with Sclerotium Gum to reduce stringiness.
| Standard INCI | Nominative Trade Ref | Typical Use (%) | Optimal pH | Electrolyte / HLB / Limit | Formulation Engineering Note |
|---|---|---|---|---|---|
Polyacrylate Crosspolymer-6 | SEPIMAX™ ZEN | 0.15 ~ 0.50 ~ 2.0% | 2.0 ~ 8.0 | High (Suspends Spicule & Low-pH Acids) | High yield stress suspends Hydrolyzed Sponge (Spicule) and stabilizes low-pH AHA/Vitamin C serums. |
Carbomer | Carbopol® 980 / Ultrez 21 | 0.05 ~ 0.25 ~ 1.0% | 5.5 ~ 9.0 | Low (Viscosity Crashes with Salts/Cations) | Requires neutralization (Arginine/Tromethamine/KOH). Incompatible with cationic actives & divalent salts. |
Ammonium Acryloyldimethyltaurate/VP Copolymer | Aristoflex® AVC | 0.10 ~ 0.50 ~ 1.5% | 4.0 ~ 9.0 | Medium (Optimal for Mild Acidic Serums) | Pre-neutralized polymer giving velvety, non-tacky aqueous gels down to pH 4.0. |
Xanthan Gum | Keltrol® CG-T | 0.05 ~ 0.25 ~ 1.0% | 2.0 ~ 12.0 | High (Stable Across Temp, Salts & pH) | Pre-disperse in Butylene Glycol/Glycerin to prevent fish-eyes; combine with Sclerotium Gum to reduce stringiness. |
Next-Gen Active Matrix · Rev.5.0 §6.2
8 Next-Generation Cosmetic Science & Active Technology Axes
Axis 1
Bio-Spicule DDS · Exosomes · PDRN
Hydrolyzed SpongeSodium DNACentella Asiatica Callus Extracellular Vesiclessh-Polypeptide-123
Formulation Note: Use high yield-value polymers (SEPIMAX ZEN) for Spicule suspension; add EVs & PDRN <40°C.
Axis 2
Signal Peptides · GHK-Cu · Neuro-Cosmetics
Copper Tripeptide-1Acetyl Hexapeptide-8Palmitoyl Tripeptide-1Carnosine
Formulation Note: NEVER mix GHK-Cu with EDTA, Phytic Acid, or L-Ascorbic Acid (Cu2+ stripping & color shift).
Axis 3
Microbiome · Postbiotics · Extremophiles
Bifida Ferment LysateGalactomyces Ferment FiltrateLactobacillus FermentSuccinic Acid
Formulation Note: High organic acid/electrolyte content crashes Carbomer; buffer Succinic Acid at pH 4.2–5.0.
Axis 4
3:1:1 Barrier Ceramides · Osmolytes
Ceramide NPBeta-SitosterolEctoinSaccharide Isomerate
Formulation Note: Melt Ceramide NP at 85–90°C in Octyldodecanol/DPG + Hydrogenated Lecithin to prevent gritty crystals.
Axis 5
4-Step Melanin Blockers · Super Antioxidants
NiacinamideTranexamic AcidAlpha-ArbutinGlutathioneErgothioneine
Formulation Note: Buffer Alpha-Arbutin at pH 4.8–6.2 to prevent Hydroquinone hydrolysis; stabilize Glutathione thiol (-SH).
Axis 6
Next-Gen Retinoids (HPR) · PHA / LHA
RetinolHydroxypinacolone RetinoateBakuchiolGluconolactoneCapryloyl Salicylic Acid
Formulation Note: EU Omnibus caps Retinol at 0.3% Face / 0.05% Body RE; Gluconolactone causes downward pH drift.
Axis 7
Green Surfactants · Eco UV Filters
Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineDiethylamino Hydroxybenzoyl Hexyl BenzoateSodium PhytateGlycolipids
Formulation Note: Bemotrizinol/DHHB are allowed up to 10% in KR/EU/CN/JP/ASEAN, but NOT listed in US FDA OTC Monograph.
Axis 8
Purified Cica Triterpenoids · K-Botanicals
MadecassosideAsiaticosideHouttuynia Cordata ExtractAllantoinGuaiazulene
Formulation Note: Limit Allantoin to ≤0.35–0.4% in clear aqueous serums to prevent sharp winter needle recrystallization.
💡 Next-Generation Micro-Channel Transdermal Delivery (DDS) & Custom Coated Bio-Spicule R&D / OEM Inquiry — UNIZ LAB Bio-Spicule Technology ↗
View Bio-Spicule Monograph →