# STEARYL HEPTANOATE (stearyl-heptanoate) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/stearyl-heptanoate
- **Standard INCI**: `STEARYL HEPTANOATE`
- **KR MFDS Standard Name**: `스테아릴헵타노에이트`
- **CAS No.**: `66009-41-4`
- **EC / EINECS No.**: `266-065-4`
- **Origin**: `synthetic`
- **Functions**: 피부컨디셔닝제, 에모리엔트
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 스테아릴헵타노에이트 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | STEARYL HEPTANOATE |
| US (PCPC / MoCRA INCI) | STEARYL HEPTANOATE |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 硬脂醇庚酸酯 |
| JP (JCIA / MHLW QD) | STEARYL HEPTANOATE  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `7975`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **reported_use** (total): 0.07~8% — 115_draft_steary.pdf (null)
- **reported_use** (leave_on): 0.07~8% — 115_draft_steary.pdf (null)
- **reported_use** (rinse_off): 0.7~3% — 115_draft_steary.pdf (null)
- **reported_use** (eye): 0.5~8% — 115_draft_steary.pdf (null)
- **reported_use** (ingestion): 3~8% — 115_draft_steary.pdf (null)
- **reported_use** (spray): 0.7~0.7% — 115_draft_steary.pdf (null)
- **reported_use** (dermal): 0.07~8% — 115_draft_steary.pdf (null)
- **reported_use** (deodorant): 0.07~0.07% — 115_draft_steary.pdf (null)
- **reported_use** (mucous): 0~0% — 116_final_stehep.pdf (null)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: STEARYL HEPTANOATE | CAS No.: 66009-41-4 | EC No.: 266-065-4
  - Origin: SYNTHETIC | Functions: Skin Conditioning, 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [STEARYL HEPTANOATE] · EU [STEARYL HEPTANOATE] · CN [硬脂醇庚酸酯] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - STEARYL HEPTANOATE functions primarily as ,  in dermatological and cosmetic formulations. Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 7975 (硬脂醇庚酸酯))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): cir (reported_use, total): 0.07~8% / cir (reported_use, leave_on): 0.07~8% / cir (reported_use, rinse_off): 0.7~3%
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [anhydrous_balm] Typical range: 1.0 ~ 8.0% (Median 8.0%, Ref: Global Starter Formulation Library Statistical Distribution (n=6, EVONIK 6)) — Anhydrous balm, oil & stick structural emollient
  - [emulsion_cream] Typical range: 1.0 ~ 3.0% (Median 3.0%, Ref: Global Starter Formulation Library Statistical Distribution (n=7, EVONIK 7)) — Emulsion cream & lotion structural / conditioning agent
  - [sun_color] Typical range: 1.0 ~ 7.0% (Median 4.5%, Ref: Global Starter Formulation Library Statistical Distribution (n=10, EVONIK 10)) — Sun care & color cosmetics dispersion / sensory modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: STEARYL HEPTANOATE
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 23064772 (2012, Int J Toxicol): Safety assessment of stearyl heptanoate and related stearyl alkanoates as used in cosmetics.

## 6. Linked PubMed Literature
- [PMID: 23064772] Safety assessment of stearyl heptanoate and related stearyl alkanoates as used in cosmetics. — *Int J Toxicol* (2012)