# SIMMONDSIA CHINENSIS SEED OIL (simmondsia-chinensis-seed-oil) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/simmondsia-chinensis-seed-oil
- **Standard INCI**: `SIMMONDSIA CHINENSIS SEED OIL`
- **KR MFDS Standard Name**: `호호바씨드오일`
- **CAS No.**: `90045-98-0`
- **EC / EINECS No.**: `289-964-3`
- **Origin**: `plant`
- **Functions**: 모발컨디셔닝제, 피부컨디셔닝제, 에모리엔트
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 호호바씨드오일 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | SIMMONDSIA CHINENSIS SEED OIL |
| US (PCPC / MoCRA INCI) | SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | — |
| JP (JCIA / MHLW QD) | SIMMONDSIA CHINENSIS SEED OIL  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `none` (Entry: `—`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- Listed within general cosmetic GMP safety thresholds.

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: SIMMONDSIA CHINENSIS SEED OIL | CAS No.: 90045-98-0 | EC No.: 289-964-3
  - Origin: PLANT | Functions: , , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL] · EU [SIMMONDSIA CHINENSIS SEED OIL] · CN [-] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - Simmondsia Chinensis Seed Oil is the fixed oil expressed or extracted from seeds of the desert shrub, Jojoba, Simmondsia chinensis, Buxaceae Classified under origin 'plant', it acts within the cosmetic vehicle or stratum corneum to deliver , ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: NONE | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. Unlisted (-))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [sun_color] Typical range: 1.0 ~ 6.0% (Median 4.0%, Ref: Global Starter Formulation Library Statistical Distribution (n=5, EVONIK 3 · GRANT 2)) — Sun care & color cosmetics dispersion / sensory modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: SIMMONDSIA CHINENSIS SEED OIL
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 41757774 (2026, J Craniofac Surg): A Translational Cell-Culture Study of Jojoba Oil: Potential Uses and Safety Considerations for Nasal Applications
  - PMID 23923639 (2013, Pharmazie): Evaluation of the mechanism of gelation of an oleogel based on a triterpene extract from the outer bark of birch

## 6. Linked PubMed Literature
- [PMID: 41757774] A Translational Cell-Culture Study of Jojoba Oil: Potential Uses and Safety Considerations for Nasal Applications — *J Craniofac Surg* (2026)
- [PMID: 23923639] Evaluation of the mechanism of gelation of an oleogel based on a triterpene extract from the outer bark of birch — *Pharmazie* (2013)