# LAURYL GLUCOSIDE (lauryl-glucoside) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/lauryl-glucoside
- **Standard INCI**: `LAURYL GLUCOSIDE`
- **KR MFDS Standard Name**: `라우릴글루코사이드`
- **CAS No.**: `110615-47-9`
- **EC / EINECS No.**: `N/A`
- **Origin**: `synthetic`
- **Functions**: 세정제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 라우릴글루코사이드 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | LAURYL GLUCOSIDE |
| US (PCPC / MoCRA INCI) | LAURYL GLUCOSIDE |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | 月桂基葡糖苷 |
| JP (JCIA / MHLW QD) | LAURYL GLUCOSIDE  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `none`
- **EU (1223/2009)**: `none`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `8374`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `none`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- Listed within general cosmetic GMP safety thresholds.

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: LAURYL GLUCOSIDE | CAS No.: 110615-47-9 | EC No.: N/A
  - Origin: SYNTHETIC | Functions: 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [LAURYL GLUCOSIDE] · EU [LAURYL GLUCOSIDE] · CN [月桂基葡糖苷] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - LAURYL GLUCOSIDE functions primarily as  in dermatological and cosmetic formulations. Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: NONE | EU: NONE | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: NONE (CN IECIC (2025) Entry No. 8374 (月桂基葡糖苷))
  - No specific Annex prohibition or numeric restriction across the 6 major jurisdictions (Permitted under general GMP safety assessment).
  - Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [aqueous_serum] Typical range: 1.6 ~ 3.0% (Median 1.6%, Ref: Global Starter Formulation Library Statistical Distribution (n=5, GRANT 3 · SEPPIC 2)) — Aqueous serum, toner & hydrogel matrix formulation component
  - [cleanser_rinse] Typical range: 3.25 ~ 20.1% (Median 8.8%, Ref: Global Starter Formulation Library Statistical Distribution (n=10, EVONIK 10)) — Rinse-off cleanser & surfactant system modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: LAURYL GLUCOSIDE
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 42289776 (2026, Contact Dermatitis): Alkyl Glucosides in Rinse-Off and Leave-On Cosmetics Available on the Dutch Market
  - PMID 42135251 (2026, Contact Dermatitis): Patch Test Results With Additions to the European Baseline Series, 2021/22-Joint European Results of the ESSCA(A) and th
  - PMID 40394829 (2025, Contact Dermatitis): Frequent Positive Patch Test Reactions to Glucosides in Children: A Call for Caution?

## 6. Linked PubMed Literature
- [PMID: 42289776] Alkyl Glucosides in Rinse-Off and Leave-On Cosmetics Available on the Dutch Market — *Contact Dermatitis* (2026)
- [PMID: 42135251] Patch Test Results With Additions to the European Baseline Series, 2021/22-Joint European Results of the ESSCA(A) and the EBS(B) Working Groups of the ESCD, and the GEIDAC(C) — *Contact Dermatitis* (2026)
- [PMID: 40394829] Frequent Positive Patch Test Reactions to Glucosides in Children: A Call for Caution? — *Contact Dermatitis* (2025)
- [PMID: 39617635] Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties — *Int J Cosmet Sci* (2025)
- [PMID: 38575135] Occurrence of alkyl glucosides in rinse-off cosmetics marketed as hypoallergenic or for sensitive skin — *Toxicol Ind Health* (2024)
- [PMID: 36839806] Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment — *Pharmaceutics* (2023)
- [PMID: 36268749] Co-reactivity of glucosides: Retrospective analysis of North American Contact Dermatitis Group Data 2019-2020 — *Contact Dermatitis* (2023)
- [PMID: 35551968] Patch testing with glucosides: The North American Contact Dermatitis Group experience, 2009-2018 — *J Am Acad Dermatol* (2022)
- [PMID: 35099073] European patch test results with audit allergens as candidates for inclusion in the European Baseline Series, 2019/20: Joint results of the ESSCA(A) and the EBS(B) working groups of the ESCD, and the GEIDAC(C) — *Contact Dermatitis* (2022)
- [PMID: 34297422] 'All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation — *Int J Cosmet Sci* (2021)
- [PMID: 42038704] Metabolic engineering of Escherichia coli for de novo production of lauryl glucoside — *Biodes Res* (2025)
- [PMID: 38750817] Comprehensive rheological analysis of structurally related acetan-like heteroexopolysaccharides from two Kozakia baliensis strains in surfactants and galactomannan blends — *N Biotechnol* (2024)