# ETHYLHEXYL TRIAZONE (ethylhexyl-triazone) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/ethylhexyl-triazone
- **Standard INCI**: `ETHYLHEXYL TRIAZONE`
- **KR MFDS Standard Name**: `에칠헥실트리아존`
- **CAS No.**: `88122-99-0`
- **EC / EINECS No.**: `402-070-1`
- **Origin**: `synthetic`
- **Functions**: 자외선차단제, 광안정제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 에칠헥실트리아존 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | ETHYLHEXYL TRIAZONE |
| US (PCPC / MoCRA INCI) | ETHYLHEXYL TRIAZONE |
| US (FDA OTC Monograph) | OCTYL TRIAZONE (UNAPPROVED OTC IN US) |
| CN (NMPA IECIC) | 乙基己基三嗪酮 |
| JP (JCIA / MHLW QD) | ETHYLHEXYL TRIAZONE  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `restricted`
- **EU (1223/2009)**: `restricted`
- **US (FDA/MoCRA)**: `banned`
- **CN (NMPA IECIC)**: `restricted` (Entry: `7709`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `restricted`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- Listed within general cosmetic GMP safety thresholds.

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: ETHYLHEXYL TRIAZONE | CAS No.: 88122-99-0 | EC No.: 402-070-1
  - Origin: SYNTHETIC | Functions: , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [ETHYLHEXYL TRIAZONE] · EU [ETHYLHEXYL TRIAZONE] · CN [乙基己基三嗪酮] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - Ethylhexyl Triazone is the heterocyclic organic compound that conforms to the formula: Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: RESTRICTED | EU: RESTRICTED | US: BANNED | CN: RESTRICTED | JP: NONE | ASEAN: RESTRICTED (CN IECIC (2025) Entry No. 7709 (乙基己基三嗪酮))
  - [CN / COMPOSITION / limited] (Max 5%): 
  - [KR / COMPOSITION / limited] (Max 5%): 
  - [EU / COMPOSITION / limited] (Max 5%): 
  - Official Safety & Historical Use Concentration (Layer 2): Quantum satis (QS) within standard cosmetic safety margins
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [sun_color] Typical range: 1.0 ~ 4.0% (Median 2.0%, Ref: Global Starter Formulation Library Statistical Distribution (n=17, EVONIK 15 · SEPPIC 2)) — Sun care & color cosmetics dispersion / sensory modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: ETHYLHEXYL TRIAZONE
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - PMID 33721254 (2021, Photochem Photobiol Sci): Sunscreens and their usefulness: have we made any progress in the last two decades?
  - PMID 30380536 (2019, Skin Pharmacol Physiol): In vivo Human Skin Penetration of the UV Filter Ethylhexyl Triazone: Effect of Lipid Microparticle Encapsulation.
  - PMID 22629203 (2012, ScientificWorldJournal): Quantification of sunscreen ethylhexyl triazone in topical skin-care products by normal-phase TLC/densitometry.

## 6. Linked PubMed Literature
- [PMID: 33721254] Sunscreens and their usefulness: have we made any progress in the last two decades? — *Photochem Photobiol Sci* (2021)
- [PMID: 30380536] In vivo Human Skin Penetration of the UV Filter Ethylhexyl Triazone: Effect of Lipid Microparticle Encapsulation. — *Skin Pharmacol Physiol* (2019)
- [PMID: 22629203] Quantification of sunscreen ethylhexyl triazone in topical skin-care products by normal-phase TLC/densitometry. — *ScientificWorldJournal* (2012)
- [PMID: 36297476] Sporopollenin Microcapsule: Sunscreen Delivery System with Photoprotective Properties. — *Pharmaceutics* (2022)
- [PMID: 25283484] Photostability of cosmetic UV filters on mammalian skin under UV exposure. — *Photochem Photobiol* (2015)