# CI 15850 (ci-15850) — Global Cosmetic Regulatory & Formulation Monograph

- **Canonical URL**: https://www.inciname.com/en/ingredients/ci-15850
- **Standard INCI**: `CI 15850`
- **KR MFDS Standard Name**: `적색201호`
- **CAS No.**: `5858-81-1`
- **EC / EINECS No.**: `227-497-9`
- **Origin**: `synthetic`
- **Functions**: 색소, 모발염색제
- **Molecular Formula / MW**: `—` (— g/mol)

## 1. 7-Track Official Regulatory Label Names
| Track | Official Label Nomenclature |
| :--- | :--- |
| KR (MFDS Standard) | 적색201호 |
| KR (Former Names) | — |
| EU (CosIng 1223/2009) | CI 15850 |
| US (PCPC / MoCRA INCI) | RED 6 / RED 7 (D&C RED NO. 6 / NO. 7) |
| US (FDA OTC Monograph) | — |
| CN (NMPA IECIC) | CI 15850 |
| JP (JCIA / MHLW QD) | CI 15850  |

## 2. Layer 1 — Global 6-Region Statutory Summary
- **KR (MFDS)**: `allowed`
- **EU (1223/2009)**: `restricted`
- **US (FDA/MoCRA)**: `none`
- **CN (NMPA IECIC)**: `allowed` (Entry: `260`)
- **JP (MHLW)**: `none`
- **ASEAN (ACD)**: `restricted`



## 3. Layer 2 — Toxicological & Historical Safe Use Concentrations
- **sccs_opinion** (non_oxidative): ≤ 0.4% — undefined (undefined)

## 4. Layer 3 — Formulation Quartiles & Compatibility
- **Optimal pH Window**: 4 – 8
- **Max Process Temp**: ≤ 50°C
- **Synergy Pairings**: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL
- **Incompatibilities**: Verify phase compatibility under extreme pH or high electrolyte loads

## 5. Academic Monograph
■ [1. Chemical Identity & International Labeling Nomenclature]
  - INCI Name: CI 15850 | CAS No.: 5858-81-1 | EC No.: 227-497-9
  - Origin: SYNTHETIC | Functions: , 
  - Physicochemical Profile: Formula      | MW /(Polymer/Complex) | /   | Ionic Nature: non-ionic | CosIng/MFDS 
  - Official Regional Label Names: US [RED 6 / RED 7 (D&C RED NO. 6 / NO. 7)] · EU [CI 15850] · CN [CI 15850] · JP [-] · JP Quasi-Drug [-]
■ [2. Dermatological Mechanism of Action & Functional Role]
  - CI 15850 is classed chemically as a monoazo colour. It conforms to the formula: Classified under origin 'synthetic', it acts within the cosmetic vehicle or stratum corneum to deliver ,  performance and structural formulation stability.
■ [3. Global 6-Jurisdiction Regulatory Status & Safety Limits (Layer 1 & Layer 2)]
  - Regional Summary: KR: ALLOWED | EU: RESTRICTED | US: NONE | CN: ALLOWED | JP: NONE | ASEAN: RESTRICTED (CN IECIC (2025) Entry No. 260 (CI 15850))
  - [EU / COMPOSITION / limited] (Max 0.4%): 
  - [EU / COMPOSITION / noted]: 
  - [KR / COMPOSITION / allowed]: 
  - [ASEAN / ADVISORY / restricted]: [ASEAN RESTRICTED] *  : (2) The insoluble barium, strontium and zirconium lakes, salts and pigments of these colouring agents shall 
  - Official Safety & Historical Use Concentration (Layer 2): sccs (sccs_opinion, non_oxidative): Max 0.4%
■ [4. Formulation Dosage Guide by Product Category (Layer 3-A)]
  - [sun_color] Typical range: 1.0 ~ 11.0% (Median 2.535%, Ref: Global Starter Formulation Library Statistical Distribution (n=6, EVONIK 6)) — Sun care & color cosmetics dispersion / sensory modifier
■ [5. Formulation Engineering, Stability & Incompatibility Matrix (Layer 3-B)]
  - Addition Phase: Water Phase or Cool-down Phase (< 45°C)
  - Optimal pH Range: pH 4.0 ~ 8.0 | Max Process Temp: Max 50°C | Electrolyte Tolerance: MEDIUM
  - Incompatibility / Caution: Verify phase compatibility under extreme pH or high electrolyte loads
  - Synergy Pairings: GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, TOCOPHEROL | Reference Trade Names: CI 15850
■ [6. Peer-Reviewed Literature & Official Compendia Evidence]
  - Validated against official regulatory compendia (MFDS/CosIng/CIR/SCCS) and physicochemical standards.

## 6. Linked PubMed Literature